Table 1 |
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|
Between-group differences in striatal connectivity |
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|
Seed |
Contrast |
Region |
Peak voxel (Talairach) |
Cluster size |
Peak t value |
||
|
|
|||||||
|
x |
y |
z |
|||||
|
|
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|
VS |
CTL > MDD |
Left subgenual ACC, medial orbitofrontal cortex |
-13 |
41 |
-4 |
40 |
3.9 |
|
MDD > CTL |
Left precuneus, posterior cingulate cortex |
-7 |
-46 |
32 |
39 |
4.1 |
|
|
Right cerebellum |
29 |
-25 |
-28 |
31 |
4.4 |
||
|
Right inferior parietal lobule |
35 |
-49 |
38 |
30 |
3.9 |
||
|
DC |
CTL > MDD |
Left medial frontal gyrus |
-7 |
53 |
-1 |
32 |
3.6 |
|
MDD > CTL |
Right middle frontal gyrus |
32 |
32 |
26 |
44 |
4.0 |
|
|
VRP |
CTL > MDD |
Left superior temporal gyrus |
-58 |
-13 |
-1 |
93 |
4.2 |
|
Left medial frontal gyrus, orbitofrontal cortex |
-16 |
35 |
-10 |
78 |
4.5 |
||
|
Right posterior insula |
44 |
-13 |
8 |
30 |
4.0 |
||
|
MDD > CTL |
Right caudate body, subgyral |
17 |
14 |
20 |
52 |
4.4 |
|
|
DCP |
CTL > MDD |
Left superior temporal gyrus |
-55 |
2 |
-7 |
50 |
5.1 |
|
Right superior temporal gyrus |
53 |
5 |
-10 |
46 |
4.6 |
||
|
Right posterior insula |
41 |
-16 |
11 |
44 |
4.4 |
||
|
Right middle temporal gyrus |
53 |
-64 |
14 |
41 |
3.8 |
||
|
MDD > CTL |
Left inferior parietal lobule, postcentral gyrus |
-46 |
-37 |
50 |
80 |
4.8 |
|
|
Right inferior parietal lobule |
41 |
-46 |
47 |
54 |
4.7 |
||
|
Right lingual gyrus |
26 |
-85 |
-13 |
38 |
4.4 |
||
|
|
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|
Voxel-wise p < 0.005, minimum cluster size = 26 voxels. ACC = anterior cingulate cortex; CTL = control; DC = dorsal caudate; DCP = dorsal caudal putamen; MDD = major depressive disorder; VRP = ventral rostral putamen; VS = ventral striatum. |
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|
Furman et al. Biology of Mood & Anxiety Disorders 2011 1:11 doi:10.1186/2045-5380-1-11 |
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