Table 3

Significant brain activation

Area

Side

x

y

z

Size (mm3)

F value

Signal change (%)


Main effect load (ROI):

Amygdala

R

27

-10

-11

2571

55.54

0.35

L

-25

-8

-12

2771

45.09

0.35

Insula

R

33

15

11

1674

54.72

0.43

L

-35

15

12

1431

59.68

0.43

FG

L

-45

-55

-14

662

45.06

0.49

Dorsal ACC

R/L

-7

43

11

10652

65.54

0.70

DMPFC

R/L

-10

43

15

8391

54.61

0.45

DLPFC

R

23

23

52

1489

42.11

0.38

L

-19

28

52

3604

57.51

0.53

Main effect load (whole brain):

Parietal cortex

R

2

-53

21

11751

62.70

0.76

L

-25

-66

34

17118

103.44

0.83

VMPFC

R/L

-7

43

9

4503

71.67

0.70

Visual cortex

R

3

-77

-7

373

23.06

0.37

L

-3

-81

-8

328

27.06

0.36

Main effect picture (whole brain):

STG

R

53

-14

-3

377

13.12

0.14

Visual cortex

R

16

-93

-5

783

20.79

0.19

L

-18

-94

-10

513

22.57

0.21

Interaction picture by group (ROI):

Amygdala

R

23

-1

-11

116

11.54

0.40

L

-27

-1

-17

108

10.15

0.35

FG

L

-42

-55

-11

179

12.11

0.32


x, y, z are the Talairach coordinates of peak voxel activation threshold: P < 0.05, corrected. Cluster threshold whole brain: 11 voxels; other thresholds: 3 to 5 voxels; voxel threshold: P < 0.005.

ACC = anterior cingulate cortex; DLPFC = dorsolateral prefrontal cortex; DMPFC = dorsomedial prefrontal cortex; FG = fusiform gyrus; ROI = region of interest; STG = superior temporal gyrus; VMPFC = ventromedial prefrontal cortex.

Straube et al. Biology of Mood & Anxiety Disorders 2011 1:12   doi:10.1186/2045-5380-1-12

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