Resolution:
standard / ## Figure 3.
5-HT. _{1A }BP_{ND }significantly moderated the correlation between 5-HT_{2A }BP_{ND }and right amygdala reactivity(A) pgPFC 5-HT_{1A }BP_{ND }moderated the correlation between pgPFC 5-HT_{2A }BP_{ND }and right amygdala reactivity. Lines indicate simple slope between pgPFC 5-HT_{2A }BP_{ND }and right amygdala reactivity at three arbitrarily chosen pgPFC 5-HT_{1A }BP_{ND }values: low (1 SD below mean (-1 SD), solid black line), mean (equivalent to mean,
red dotted line) and high (1 SD above mean (+1 SD), green dotted line). (B) sgPFC 5-HT_{1A }BP_{ND }significantly moderated the association between sgPFC 5-HT_{2A }BP_{ND }and right amygdala reactivity. Lines indicate simple slope between sgPFC 5-HT_{2A }BP_{ND }and right amygdala reactivity at three arbitrarily chosen sgPFC 5-HT_{1A }BP_{ND }values: low (-1 SD, solid black line), mean (red dotted line) and high (+1 SD, green
dotted line). *Indicates simple slope, P < 0.05; 5-HT = serotonin; a.u. = arbitrary units; BP_{ND }= binding potential, non-displaceable; pgPFC = pregenual prefrontal cortex; sgPFC
= subgenual prefrontal cortex.
Fisher |