Table 1 |
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|
Demographic and clinical characteristics of the seven voxel-based diffusion tensor imaging studies included in our meta-analysisa |
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|
Characteristics |
Kieseppä et al. [18] |
Blood et al. [24] |
Zhu et al. [58] |
Wu et al. [25] |
Korgaonkar et al. [60] |
Jia et al. [26] |
Abe et al. [59] |
|
|
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|
Number of patients |
16 |
22 |
25 |
23 |
29 |
52 |
21 |
|
Number of controls |
20 |
22 |
25 |
21 |
39 |
52 |
42 |
|
Mean age of patients, years |
48.4 |
36.3 |
20.6 |
31.4 |
40.5 |
34.5 |
48.1 |
|
Mean age of controls, years |
42 |
35.3 |
20.3 |
30.4 |
29.6 |
37.1 |
48 |
|
Patient sex, % female |
87.5 |
54.5 |
60 |
65.5 |
58.7 |
51.9 |
47.6 |
|
Control sex, % female |
50 |
54.5 |
60 |
56.5 |
53.8 |
54 |
47.6 |
|
Late-life depression |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Major depressive disorder |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
|
Anxiety in patients (0 = no, 1 = yes) |
NA |
0 |
0 |
0 |
NA |
0 |
0 |
|
Treatment, % patients receiving medication at time of study |
81 |
31.8 |
0 |
0 |
0 |
0 |
90.5 |
|
Mean illness duration, years |
14.1 |
NA |
13.6 |
2.2 |
NA |
3.3 |
6 |
|
Mean BDI score |
26.3 |
NA |
NA |
NA |
NA |
NA |
NA |
|
Hamilton score |
NA |
NA |
NA |
21.8 |
19.1 |
23 |
9.2 |
|
IDS-SR score |
NA |
36 |
NA |
NA |
NA |
NA |
NA |
|
Mean CES-D score |
NA |
NA |
35.48 |
NA |
NA |
NA |
NA |
|
Illness severity |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
|
|
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|
aBDI, Beck Depression Inventory; IDS-SR, Inventory of Depressive Symptoms-Self-Rated; CES-D, Center for Epidemiologic Studies Depression Scale. NA, not applicable. |
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|
Murphy and Frodl Biology of Mood & Anxiety Disorders 2011 1:3 doi:10.1186/2045-5380-1-3 |
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