Table 1

Demographic and clinical characteristics of the seven voxel-based diffusion tensor imaging studies included in our meta-analysisa

Characteristics

Kieseppä

et al. [18]

Blood

et al. [24]

Zhu

et al. [58]

Wu

et al. [25]

Korgaonkar

et al. [60]

Jia

et al. [26]

Abe

et al. [59]


Number of patients

16

22

25

23

29

52

21

Number of controls

20

22

25

21

39

52

42

Mean age of patients, years

48.4

36.3

20.6

31.4

40.5

34.5

48.1

Mean age of controls, years

42

35.3

20.3

30.4

29.6

37.1

48

Patient sex, % female

87.5

54.5

60

65.5

58.7

51.9

47.6

Control sex, % female

50

54.5

60

56.5

53.8

54

47.6

Late-life depression

0

0

0

0

0

0

0

Major depressive disorder

1

1

1

1

1

1

1

Anxiety in patients (0 = no, 1 = yes)

NA

0

0

0

NA

0

0

Treatment, % patients receiving medication at time of study

81

31.8

0

0

0

0

90.5

Mean illness duration, years

14.1

NA

13.6

2.2

NA

3.3

6

Mean BDI score

26.3

NA

NA

NA

NA

NA

NA

Hamilton score

NA

NA

NA

21.8

19.1

23

9.2

IDS-SR score

NA

36

NA

NA

NA

NA

NA

Mean CES-D score

NA

NA

35.48

NA

NA

NA

NA

Illness severity

2

2

3

3

3

3

1


aBDI, Beck Depression Inventory; IDS-SR, Inventory of Depressive Symptoms-Self-Rated; CES-D, Center for Epidemiologic Studies Depression Scale. NA, not applicable.

Murphy and Frodl Biology of Mood & Anxiety Disorders 2011 1:3   doi:10.1186/2045-5380-1-3

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