Table 2

Significant regional differences in fractional anisotropy values of the left superior longitudinal fasciculus and right inferior fronto-occipital fasciculus were found in patients with major depressive disorder compared to controls^a

Region

Talairach coordinates

SDM value

Uncorrected

P value

Voxel number

Breakdown

(number of voxels)

Left SLF, inferior parietal lobe

-38, -38, 26

-0.271

0.00023

179

Inferior parietal lobe (63)

Subgyral parietal lobe (70)

Insula (25)

Supramarginal gyrus (12)

Extranuclear (6)

Subgyral frontal lobe (1)

Superior temporal gyrus (2)

Right inferior fronto-occipital fasciculus

30, -56, 2

0.125

0.000097

33

Subgyral occipital lobe (8)

Subgyral temporal lobe (11)

Lingual gyrus occipital lobe (4)

Middle occipital gyrus (4)

Extranuclear (5)

Middle occipital gyrus (1)

^aSDM, Signed Differential Mapping; SLF, superior longitudinal fasciculus.

Murphy and Frodl Biology of Mood & Anxiety Disorders 2011 1:3   doi:10.1186/2045-5380-1-3