Post-traumatic stress disorder (PTSD) symptom severity correlates with the magnitude of unconditioned stimulus (US) reactivity. Positive correlations between blood oxygenation level-dependent (BOLD) US signal in the right anterior insula/inferior frontal gyrus and Clinician-Administered PTSD Scale (CAPS) score in the 19 subjects with PTSD investigated. The correlation map is displayed at a threshold of T > 4 on a template magnetic resonance imaging (MRI) scan.
Linnman et al. Biology of Mood & Anxiety Disorders 2011 1:8 doi:10.1186/2045-5380-1-8