Figure 2.

Criteria of validity for animal models. A comparison between the general process of the human disease (on the lower plane) and its animal model (on the higher plan). The orthogonal black arrows link the crucial points of similarity between the parallel processes and represent the different criteria of overall validity for animal models (or the various kinds of validity according to which an animal model ought to be designed).

Belzung and Lemoine Biology of Mood & Anxiety Disorders 2011 1:9   doi:10.1186/2045-5380-1-9
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