Table 1 |
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|
Demographic and clinical data of participants |
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|
FHN (n = 14) |
FHP (n = 10) |
MDD (n = 14) |
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|
|
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|
Χ2 |
df |
P |
|||||||
|
Gender (female/male) |
4/10 |
6/4 |
9/5 |
4.1 |
2/36 |
0.12 |
|||
|
Handedness (right/left/ambidextrous) |
14/0/0 |
8/2/0 |
12/1/1 |
5 |
4/34 |
0.3 |
|||
|
|
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|
Mean |
SD |
Mean |
SD |
Mean |
SD |
F |
df |
P |
|
|
|
|||||||||
|
Age (years) |
35 |
9.4 |
33 |
10 |
41.2 |
10.3 |
2.2 |
2/36 |
ns |
|
Weight (kg) |
74 |
18 |
63.3 |
5 |
73.6 |
13 |
1.9 |
2/36 |
ns |
|
Illness duration (years) |
- |
- |
- |
- |
16 |
10 |
- |
- |
- |
|
HDRS score |
0.7 |
0.9 |
4.8 |
5.3 |
24.8 |
5 |
125 |
2/36 |
< 0.001a |
|
Age of onset |
- |
- |
- |
- |
25 |
11 |
- |
- |
- |
|
|
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|
Median |
MR |
Median |
MR |
Median |
MR |
4.7 |
df |
P |
|
|
|
|||||||||
|
Alcohol intake per week (g) |
16 |
16 |
60 |
26 |
28 |
18 |
4.6 |
2/36 |
ns |
|
Cigarettes per day |
0 |
15 |
1 |
23.5 |
0 |
21 |
5.7 |
2/36 |
ns |
|
|
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|
aThere was a difference between the MDD patients and either the FHN (P < 0.001) or the FHP (P < 0.001) subjects in the HDRS; bF-score from analysis of variance. df: degrees of freedom; MDD: patients with major depressive disorder; FHN: healthy participants without family history of MDD; FHP: healthy participants with family history of MDD; HDRS: Hamilton Depression Rating Scale for Depression; ns: not significant; SD: standard deviation, Χ2: Chi-squared score, MR: Mean Rank |
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|
Amico et al. Biology of Mood & Anxiety Disorders 2012 2:1 doi:10.1186/2045-5380-2-1 |
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