Table 1

Demographic and clinical data of participants

FHN

(n = 14)

FHP

(n = 10)

MDD

(n = 14)


Χ2

df

P

Gender (female/male)

4/10

6/4

9/5

4.1

2/36

0.12

Handedness (right/left/ambidextrous)

14/0/0

8/2/0

12/1/1

5

4/34

0.3


Mean

SD

Mean

SD

Mean

SD

F

df

P


Age (years)

35

9.4

33

10

41.2

10.3

2.2

2/36

ns

Weight (kg)

74

18

63.3

5

73.6

13

1.9

2/36

ns

Illness duration (years)

-

-

-

-

16

10

-

-

-

HDRS score

0.7

0.9

4.8

5.3

24.8

5

125

2/36

< 0.001a

Age of onset

-

-

-

-

25

11

-

-

-


Median

MR

Median

MR

Median

MR

4.7

df

P


Alcohol intake per week (g)

16

16

60

26

28

18

4.6

2/36

ns

Cigarettes per day

0

15

1

23.5

0

21

5.7

2/36

ns


aThere was a difference between the MDD patients and either the FHN (P < 0.001) or the FHP (P < 0.001) subjects in the HDRS; bF-score from analysis of variance. df: degrees of freedom; MDD: patients with major depressive disorder; FHN: healthy participants without family history of MDD; FHP: healthy participants with family history of MDD; HDRS: Hamilton Depression Rating Scale for Depression; ns: not significant; SD: standard deviation, Χ2: Chi-squared score, MR: Mean Rank

Amico et al. Biology of Mood & Anxiety Disorders 2012 2:1   doi:10.1186/2045-5380-2-1

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