Table 5 |
|||||||||
| Change-point analysis of the BOLD responses to the social evaluative threat task of participants with and without social anxiety disorder | |||||||||
| Region | x | y | z | voxels | vol (mm3) | Peak t | change-point onset | change-point offset | comorbid (~,>,<) social anxiety |
| Social Anxiety > No Social Anxiety | |||||||||
| Instructions | |||||||||
| Cerebellum: Declive* | 8 | −58 | −14 | 325 | 8775 | 12.52 | 66 | 102 | < |
| r. Lingual G.* | 26 | −74 | −2 | 15 | 405 | 5.34 | 69 | 79 | < |
| r. Superior Temporal G. | 56 | −38 | 4 | 31 | 837 | 7.68 | 66 | 83 | ~ |
| Early Speech Prep | |||||||||
| No suprathreshold voxels | |||||||||
| Late Speech Prep | |||||||||
| No suprathreshold voxels | |||||||||
| Recovery | |||||||||
| r. Cerebellum: Declive* | 26 | −56 | −20 | 142 | 3834 | 9.03 | 164 | 174 | < |
| l. Cerebellum: Declive | −20 | −62 | −20 | 83 | 2241 | 7.45 | 163 | 171 | ~ |
| No Social Anxiety > Social Anxiety | |||||||||
| Instructions | |||||||||
| l. Insula | −32 | 8 | −4 | 54 | 1458 | −7.21 | 68 | 80 | |
| r. Precentral G. | 50 | −8 | 22 | 151 | 4077 | −6.6 | 67 | 81 | ~ |
| l. Inferior Frontal G.* | −52 | 8 | 10 | 66 | 1782 | −6.62 | 68 | 86 | > |
| r. Middle Frontal G. | 34 | 52 | 8 | 19 | 513 | −7.21 | 68 | 82 | ~ |
| Cingulate G. | 4 | −8 | 34 | 237 | 6399 | −7.91 | 66 | 91 | |
| l. Cingulate/Supramarginal G. | −26 | −26 | 38 | 159 | 4293 | −6.94 | 66 | 81 | ~ |
| Early Speech Prep | |||||||||
| No suprathreshold voxels | |||||||||
| Late Speech Prep | |||||||||
| No suprathreshold voxels | |||||||||
| Recovery | |||||||||
| r. Insula | 44 | −2 | −2 | 103 | 2781 | −6.67 | 164 | 184 | ~ |
| l. Insula | −40 | 4 | 2 | 124 | 3348 | −7.4 | 164 | 184 | ~ |
| l. Postcentral G. | −38 | −20 | 38 | 29 | 783 | −6.89 | 166 | 177 | ~ |
Note. These clusters were masked with the clusters that exhibited group average activation differences during the social evaluative threat task. vol = volume; G. = Gyrus. 1 Post-hoc group contrasts that test whether comorbid participants exhibited similar (~; not significantly different from each other, but both groups are different than control participants), greater (>), or less (<) activation than participants with pure social anxiety (p < .05). The lack of a symbol means that comorbid participants did not exhibit significantly different activation than control participants and participants with pure social anxiety.
* Those regions for which comorbid participants’ activation significantly differed from both pure depression and pure social anxiety groups.
Waugh et al. Biology of Mood & Anxiety Disorders 2012 2:11 doi:10.1186/2045-5380-2-11
