Research
Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation
1 Department of Psychiatry, New Haven, CT, 06511, USA
2 Keck Foundation Biotechnology Biostatistics Resource, New Haven, CT, 06511, USA
3 Center for Genome Analysis, New Haven, CT, 06511, USA
4 Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, 06511, USA
5 Neuroscience Global Clinical Research, Bristol-Myers Squibb, Wallingford, CT, 06492-1996, USA
Biology of Mood & Anxiety Disorders 2012, 2:15 doi:10.1186/2045-5380-2-15
Published: 12 September 2012Additional files
Additional file 1:
Table S1. Fold difference and p-value for each of 127 genes, grouped by cluster, that showed a significant group x time interaction (i.e. difference in degree or direction of change between lithium-responders and non-responders) after FDR correction for multiple testing , and a fold-difference ≥ 1.3 between lithium responders and non-responders at least one time-point after treatment initiation.
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