Scatter plot showing individual differences in activation in the medial prefrontal cortex (mPFC) for the regulate negative > look negative contrast based on global sleep quality scores for the PSQI. Worse sleep predicted less mPFC cluster activation (b = -.190, p = .03). Filled circles indicate participants who reported using sleep medication within the last month.
Minkel et al. Biology of Mood & Anxiety Disorders 2012 2:22 doi:10.1186/2045-5380-2-22