Table 1

Global gray matter volumes reported in seven studies on obsessive-compulsive disorder

Reference

Patients

Controls

Patients + controls

Difference

Effect size


Number

Volume ± SD

Number

Volume ± SD

N

Variance

Estimate

Variance

Estimate

Variance


Study 1

[46]

18

773 ± 56

18

822 ± 56

36

3,114

-49

346

-0.854

0.122

Study 2

[47]

55

685 ± 74

50

708 ± 72

105

5,323

-23

203

-0.313

0.039

Study 3

[48]

25

850 ± 83

25

834 ± 71

50

5,997

+16

480

0.196

0.080

Study 4

[49]

72

739 ± 82

72

763 ± 78

144

6,404

-24

178

-0.298

0.028

Study 5

[50]

37

776 ± 69

26

747 ± 68

63

4,680

+29

307

0.418

0.067

Study 6

[51]

19

827 ± 44

15

836 ± 63

34

3,041

-9

363

-0.179

0.120

Study 7

[52]

71

740 ± 66

71

738 ± 63

142

4,119

+2

116

0.035

0.028


All volumes are in milliliters. SD: standard deviation.

Radua and Mataix-Cols Biology of Mood & Anxiety Disorders 2012 2:6   doi:10.1186/2045-5380-2-6

Open Data