Table 1 |
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|
Global gray matter volumes reported in seven studies on obsessive-compulsive disorder |
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|
Reference |
Patients |
Controls |
Patients + controls |
Difference |
Effect size |
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|
|
|||||||||||
|
Number |
Volume ± SD |
Number |
Volume ± SD |
N |
Variance |
Estimate |
Variance |
Estimate |
Variance |
||
|
|
|||||||||||
|
Study 1 |
[46] |
18 |
773 ± 56 |
18 |
822 ± 56 |
36 |
3,114 |
-49 |
346 |
-0.854 |
0.122 |
|
Study 2 |
[47] |
55 |
685 ± 74 |
50 |
708 ± 72 |
105 |
5,323 |
-23 |
203 |
-0.313 |
0.039 |
|
Study 3 |
[48] |
25 |
850 ± 83 |
25 |
834 ± 71 |
50 |
5,997 |
+16 |
480 |
0.196 |
0.080 |
|
Study 4 |
[49] |
72 |
739 ± 82 |
72 |
763 ± 78 |
144 |
6,404 |
-24 |
178 |
-0.298 |
0.028 |
|
Study 5 |
[50] |
37 |
776 ± 69 |
26 |
747 ± 68 |
63 |
4,680 |
+29 |
307 |
0.418 |
0.067 |
|
Study 6 |
[51] |
19 |
827 ± 44 |
15 |
836 ± 63 |
34 |
3,041 |
-9 |
363 |
-0.179 |
0.120 |
|
Study 7 |
[52] |
71 |
740 ± 66 |
71 |
738 ± 63 |
142 |
4,119 |
+2 |
116 |
0.035 |
0.028 |
|
|
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|
All volumes are in milliliters. SD: standard deviation. |
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|
Radua and Mataix-Cols Biology of Mood & Anxiety Disorders 2012 2:6 doi:10.1186/2045-5380-2-6 |
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