Table 3 |
|||||
| BOLD responses from both our anatomical ROI analyses and our functional ROI analyses comparing males and women during the different phases of the study | |||||
| Bold responses from anatomical ROI analyses | |||||
| Phase | condition | regions | coordinates | z | P(≤) |
| conditioning | F > M | L-dACC | −8,38,26 | 3.54 | 0.001 |
| R-rACC | 12,58,4 | 3.44 | 0.001 | ||
| Amyg | 28,-6,-16 | 3.08 | 0.001 | ||
| M > F | non | ||||
| Ext learning | F > M | non | |||
| M > F | non | ||||
| Ext Recall | F > M | L-insula | −46,-2,-10 | 3.15 | 0.002 |
| M > F | L-rACC | −6,32,-4 | 2.79 | 0.005 | |
| BOLD responses from functional ROI analyses | |||||
| Conditioning | F > M | non | |||
| M > F | non | ||||
| Ext Learning | F > M | dACC | 8,12,18 | 3.62 | 0.001 |
| dACC | 10,14,20 | 3.27 | 0.001 | ||
| mPFC | 28,54,-4 | 3.33 | 0.001 | ||
| L-hypotha | −8,2,-6 | 2.25 | 0.024 | ||
| M < F | hypothalamus | 6,4,-6 | 2.44 | 0.015 | |
| Ext Recall | F > M | non | |||
| M > F | L-rACC | −6,42,-16 | 3.16 | 0.001 | |
ROIs are based on sexually dimorphic areas of the stress response circuitry identified by Goldstein and colleagues (2010).
Lebron-Milad et al. Biology of Mood & Anxiety Disorders 2012 2:7 doi:10.1186/2045-5380-2-7