Table 1

Functional neuroimaging studies included in meta-analysis
Study PTSD TC* NTC** Type of trauma Contrast used in meta-analysis Scanning task Imaging method Design
Symptom Provocation Whole Brain Analyses (10)
Bremner et al. 1999a 10 10 Combat Combat vs. neutral pictures and sounds View and listen PET Block
Bremner et al. 1999b 10 12 SA+ Childhood abuse vs. neutral scripts Image and remember event PET Block
Britton et al. 2005 16 15 Combat Combat vs. neutral scripts Listen and maintain evoked emotional state PET Block
Hou et al. 2007 10 7 Mining accident Mining accident vs. neutral pictures View fMRI Block
Lanius et al. 2001 9 9 Mixed Trauma scripts vs. baseline Listen and remember event fMRI Block
Lanius et al. 2002 7 10 SA (1 MVA) + Trauma scripts vs. baseline Listen and remember event fMRI Block
Lanius et al. 2003 10 10 Mixed Trauma scripts vs. baseline Listen and remember event fMRI Block
Lanius et al. 2007 26 16 MVA+ Trauma vs. neutral scripts Listen and remember event fMRI Block
Shin et al. 1999 8 8 SA+ Sexual abuse vs. neutral scripts Recall and imagine contents of script PET Block
Shin et al. 2004 17 19 Combat Combat vs. neutral scripts Recall and imagine contents of script PET Block
Symptom Provocation ROI Analyses (2)
Frewen et al. 2008 25 16 MVA+ Trauma vs. neutral scripts Listen to and image script fMRI Block
Protopopescu et al. 2005 9 14 SA, PA+ PTSD vs. neutral words Read word fMRI Block
Cognitive-Emotional Whole Brain Analyses (12)
Bremner et al. 2003 10 11 SA+ Negative emotional vs. neutral word pairs Declarative memory task PET Block
Bremner et al. 2004 12 9 SA+ Negative emotional vs. neutral words Stroop task PET Block
Brunetti et al. 2010 10 10 Assault Negative emotional vs. neutral IAPS pictures Visuo-attentional task fMRI Block
Felmingham et al. 2010 23 21 Mixed Fearful vs. neutral faces Backward masking task fMRI Block
Fonzo et al. 2010 12 12 IPV+ Fearful vs. happy faces Emotional face matching task fMRI Block
Kim et al. 2008 12 12 Fire Fearful vs. neutral faces Same-different judgment task fMRI Event-related
Sakamoto et al. 2005 16 16 Mixed Traumatic vs. neutral images View stimuli below perceptual threshold fMRI Block
Shin et al. 2005 13 13 Combat, fire Fearful vs. happy faces Overt passive viewing task fMRI Block
Thomaes et al. 2009 9 9 SA, PA+ Negative words vs. baseline Word classification task fMRI Event-related
Whalley et al. 2009 16 16 16 Mixed Negative vs. neutral background pictures with neutral foreground pictures Episodic memory retrieval task fMRI Event-related
Williams et al. 2006 13 13 Mixed Fearful vs. neutral faces Overt fear perception task fMRI Block
Hou et al. 2007 Same Hou et al. 2007 article as the one listed above (in addition to symptom provocation coordinates, article reported coordinates from a short-term memory recall task)
Cognitive-Emotional ROI Analyses (6)
Bryant et al. 2008 15 15 Mixed Fearful vs. neutral faces View stimuli below conscious threshold fMRI Block
Phan et al. 2006 16 15 Combat Negative vs. neutral IAPS pictures View and rate pictures PET Block
Rauch et al. 2000 8 8 Combat Fearful vs. positive faces Masked faces paradigm fMRI Block
Felmingham et al. 2010 Same as whole brain article above
Fonzo et al. 2010 Same as whole brain article above
Williams et al. 2006 Same as whole brain article above

*TC: trauma exposed controls without PTSD. **NTC: non-traumatized controls.

+SA: sexual abuse/assault; PA: physical abuse/assault; MVA: motor vehicle accident; NSA: non sexual assault; IPV: intimate partner violence.

Hayes et al.

Hayes et al. Biology of Mood & Anxiety Disorders 2012 2:9   doi:10.1186/2045-5380-2-9

Open Data