Table 2

Number of activation foci included in between-group analyses
Study P > C+ C > P+ Statistical threshold
Symptom Provocation Whole Brain Analyses
Bremner et al. 1999a 5 5 P < .001
Bremner et al. 1999b 9 19 P < .001
Britton et al. 2005 -- 1 P < .005
Hou et al. 2007 1 9 P < .005
Lanius et al. 2001 -- 4 P < .001
Lanius et al. 2002 9 3 P < .001, > 10 voxels
Lanius et al. 2003 -- 9 P < .001, > 10 voxels
Lanius et al. 2007 -- 2 P < .05 cor., > 10 voxels
Shin et al. 1999 4 14 P < .001
Shin et al. 2004 1 3 P < .001
Symptom Provocation ROI Analyses
Protopopescu et al. 2005 1 -- P < .01 cor.
Frewen et al. 2008 -- 3 P < .05, > 10 voxels
Cognitive-Emotional Whole Brain Analyses
Bremner et al. 2003 15 14 P < .01 cor.
Bremner et al. 2004 2 6 P < .005 cor., > 65 voxels
Brunetti et al. 2010 6 3 P < .001
Felmingham et al. 2010 1 -- P < .001, > 10 voxels
Fonzo et al. 2010 3 1 P < .05
Kim et al. 2007 7 6 P < .001
Sakamoto et al. 2005 1 4 P < .01
Shin et al. 2005 4 4 P < .001
Thomaes et al. 2009 2 -- P < .001
Whalley et al. 2009 3 1 P < .001
Williams et al. 2006 7 1 P < .001
Hou et al. 2007* -- 2 P < .005
Cognitive-Emotional ROI Analyses
Bryant et al. 2008 4 -- P < .05, > 3 voxels
Phan et al. 2006 -- 1 P < .005 cor.
Rauch et al. 2000 1 -- P < .05
Felmingham et al. 2010** 9 -- P < .001, > 10 voxels
Fonzo et al. 2010** 2 -- P < .05
Williams et al. 2006** 2 4 P < .001
Total SP foci 30 72
Total cognitive-emotional foci 69 47
Total number of foci 99 119

+P > C: PTSD patients > Controls; C > P: Controls > PTSD patients.

*Paper also reported symptom provocation coordinates.

**Papers also reported whole brain coordinates.

cor. = corrected for multiple comparisons.

Hayes et al.

Hayes et al. Biology of Mood & Anxiety Disorders 2012 2:9   doi:10.1186/2045-5380-2-9

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