Table 4

Between-group comparison results of symptom provocation articles and cognitive-emotional articles
Region Hemisphere Talairach BA Volume (mm3)
x y z
SYMPTOM PROVOCATION
    PTSD > Controls
Whole Brain Analysis
Dorsal ACC R 15.38 37.69 16.96 32 344
Mid/Dorsal ACC R 2.65 −8.91 33.77 24 296
Mid/Dorsal ACC R 0.3 −19.11 37.4 24 104
Whole Brain + ROI Analysis
Dorsal ACC R 15.38 37.69 16.96 32 344
Mid/Dorsal ACC R 2.65 −8.91 33.77 24 296
    Controls > PTSD
Whole Brain Analysis
Medial Frontal Gyrus (vmPFC) R 3.32 36.07 −6.42 11 1152
Thalamus R 12 −12 2 -- 648
Thalamus L −4.02 −14.02 17.98 -- 648
Inferior Frontal Gyrus R 45.62 14.54 8.65 44 480
Precuneus R 25.83 −84.66 39.57 19 296
Inferior Frontal Gyrus R 41.77 40.46 7.18 46 216
Medial Frontal Gyrus R 3.94 50.11 7.37 10 208
Whole Brain + ROI Analysis
Medial Frontal Gyrus (vmPFC) R 3.34 36.13 −6.34 11 1168
Thalamus R 12 −12 2 -- 648
Thalamus L −4.03 −14.01 17.97 -- 648
Medial Frontal Gyrus R 0.63 47.89 5.66 10 504
Inferior Frontal Gyrus R 45.69 14.62 8.52 44 464
Precuneus R 25.83 −84.66 39.57 19 296
Inferior Frontal Gyrus R 41.77 40.46 7.18 46 216
COGNITIVE- EMOTIONAL
    PTSD > Controls
Whole Brain Analysis
Supplementary Motor Area L −22.13 −1.49 57.27 6 128
Supplementary Motor Area L −25.39 2.02 40.31 6 104
Whole Brain + ROI Analysis
Amygdala R 22.93 1.03 −13.28 -- 1376
Amygdala L −27.21 −0.16 −17.37 -- 840
Medial Frontal Gyrus (dmPFC) R 0.98 31.46 37.87 8 224
    Controls > PTSD
Whole Brain Analysis
Pregenual ACC (vmPFC) L −13.93 49.87 −2.12 32 400
Medial Frontal Gyrus (dmPFC) R 10.63 40.6 23.03 9 272
Whole Brain + ROI Analysis
Medial Frontal Gyrus (dmPFC) R 11.17 41.96 21.25 9 984
Pregenual ACC (vmPFC) L −13.97 49.76 −2.16 32 384

P < 0.05 FDR-corrected, activation extent ≥ 100 mm3. ACC = anterior cingulate cortex, BA = Brodman area, dmPFC = dorsomedial prefrontal cortex, L = left, R = right, vmPFC = ventromedial prefrontal cortex.

Hayes et al.

Hayes et al. Biology of Mood & Anxiety Disorders 2012 2:9   doi:10.1186/2045-5380-2-9

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