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Volume 2 (2012) - November 2012

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Review   Open Access

The role of the amygdala in the pathophysiology of panic disorder: evidence from neuroimaging studies

Jieun E Kim, Stephen R Dager, In Kyoon Lyoo Biology of Mood & Anxiety Disorders 2012, 2:20 (20 November 2012)

Abstract | Full text | PDF | PubMed

Brief Report   Open Access Highly Accessed

Neural responses to threat and reward interact to predict stress-related problem drinking: A novel protective role of the amygdala

Yuliya S Nikolova, Ahmad R Hariri Biology of Mood & Anxiety Disorders 2012, 2:19 (14 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

FMRI imaging has been used to identify a relationship between stress and threat and reward neurocircuitry. Problem drinking in association with stressful life events is only likely to develop in individuals with both highly reactive reward circuitry (i.e. ventral striatum), and hypo-reactive threat circuitry (i.e. amygdala). [Image credit: Wikimedia commons Justinc]