Table 2

Faces task: differential and common BOLD responses for Reappraise versus React
x y z Vol (mm3) t-value
Between-group differential responses
SAD > HC: Reappraise > React-none
HC > SAD: Reappraise > React
Left inferior frontal gyrus -34, 25, 15 426 3.56
Dorsal anterior cingulate gyrus 0, 18, 33 372 3.46
Left lateral orbitofrontal cortex -31, 52, -6 372 3.63
Within-group responses1
SAD only: Reappraise > React
Right cuneus 3, -82, 39 57,444 3.39
(Left cuneus, bilateral precuneus, bilateral lingual gyrus, bilateral parahippocampal gyrus)
Left superior temporal gyrus BA38 -48, 28, -19 3,191 3.30
Left Superior Temporal Gyrus BA21 -65, -20, -2 1,330 3.76
Left dorsomedial PFC -3, 11, 63 1,330 3.38
Left precentral gyrus BA6 -52, -3, 29 1,170 3.61
Right middle temporal gyrus BA21 55, -3, -9 1,117 3.64
Left putamen -21, 4, 5 1,117 4.26
Right superior temporal gyrus BA38 45, 21, -16 1,011 3.56
Left inferior frontal gyrus BA45 -55, 31, 8 532 3.09
Left superior temporal gyrus -65, -13, -2 479 3.72
Left thalamus -14, -13, -8 426 4.05
Right thalamus 14, -13, 12 426 4.15
Right superior temporal gyrus 38, 7, -12 372 3.12
Left middle temporal gyrus -55, -10, -9 372 3.75
HC only: Reappraise > React
Left lingual gyrus -3, -58, 5 67,125 7.08
(Right lingual gyrus, bilateral cuneus, bilateral precuneus, bilateral parahippocampus)
Left dorsomedial PFC -3, 4, 63 3,191 3.73
Left precentral gyrus BA4/6 -55, -3, 50 1,808 3.21
Left supramarginal gyrus BA40 -65, -48, 19 1,011 3.83
Left superior temporal gyrus -55, -17, -2 798 5.05
Left inferior frontal gyrus -52, 25, -6 745 3.62
Left superior temporal gyrus BA22 -62, -34, 12 745 3.10
Right superior temporal gyrus BA38 41, -24, 1 691 3.53
Left superior temporal gyrus BA38 -52, 14, -9 585 3.40
Right precentral gyrus BA6 62, 4, 19 426 3.69
Left middle temporal gyrus -55, -6, -6 426 4.69

1Regions showing increased BOLD response during Reappraise versus React in both SAD and HC (common responses) are marked in italics.

Note. t-value threshold ≥2.932, voxel P <0.005, minimum cluster volume threshold ≥244 mm3 (6 voxels × 3.438 mm3), cluster P <0.01.

BA = Brodmann area, xyz = Talairach and Tournoux coordinates of maximum BOLD signal intensity voxel.

Ziv et al.

Ziv et al. Biology of Mood & Anxiety Disorders 2013 3:20   doi:10.1186/2045-5380-3-20

Open Data