Table 3

Criticism task: differential and common BOLD responses for Reappraise versus React
x y z Vol (mm3) t-value
Between-group differential responses
SAD > HC: Reappraise > React - none
HC > SAD: Reappraise > React
Left fusiform gyrus -24, -68, -12 904 3.16
Right cerebellum 3, -68, -9 745 3.01
Right fusiform gyrus 24, -75, -12 585 4.13
Left putamen -28, -13, -6 479 2.96
Left lingual gyrus -7, -75, -12 426 3.28
Right cerebellum 24, -51, -16 372 2.94
Right cerebellum 17, -58, -12 372 3.04
Within-group responses1
SAD only: Reappraise > React
Left dorsomedial PFC -3, 11, 60 2,500 4.27
Left dorsolateral PFC -48, 7, 50 1,170 3.59
Right precuneus 17, -55, 63 745 3.36
Right parahippocampal gyrus 24, -44, -6 372 3.25
HC only: Reappraise > React
Left lingual gyrus -3, -58, 5 13,936 3.21
(Right lingual gyrus, bilateral fusiform gyrus, bilateral cerebellum)
Right precentral gyrus BA6/BA4 28, -17, 63 9,308 3.14
Left dorsomedial PFC -3, 11, 67 6,915 3.34
Left dorsolateral PFC -52, 4, 50 3,776 3.83
Left supramarginal gyrus -62, -58, 15 3,351 4.09
Left middle frontal gyrus -45, 21, 29 2,234 3.42
Right superior parietal cortex/precuneus 24, -55, 60 2,128 3.31
Left superior parietal cortex/precuneus -24, -75, 53 1,808 4.18
Left inferior frontal gyrus BA45 -55, 25, -2 1,755 3.25
Left medial frontal gyrus -3, 7, 43 1,170 3.15
Right precuneus 28, -72, 22 1,064 3.45
Left superior temporal gyrus -65, -174, -2 1,064 3.79
Left middle frontal gyrus -31, 49, 12 851 3.14
Left precuneus -31, -89, 19 745 3.34
Left anterior insula -48, 11, 5 745 3.53
Left precentral gyrus BA4 -24, -24, 56 691 3.56
Left thalamus -3, -3, 12 638 3.34
Left angular gyrus -48, -61, 36 585 3.12
Left superior temporal gyrus -38, -55, 29 319 3.38
Left putamen -31, -10, -2 319 3.28
Left middle temporal gyrus -52, -34, 5 319 3.33

1Regions showing increased BOLD response during Reappraise versus React in both SAD and HC (common responses) are marked in italics.

Note. t-value threshold ≥2.93, voxel P <0.005, minimum cluster volume threshold ≥244 mm3 (6 voxels × 3.438 mm3), cluster P <0.01.

BA = Brodmann area, xyz = Talairach and Tournoux coordinates of maximum BOLD signal intensity voxel.

Ziv et al.

Ziv et al. Biology of Mood & Anxiety Disorders 2013 3:20   doi:10.1186/2045-5380-3-20

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