Maltreated animals have reduced fractional anisotropy (FA) in left occipital white matter (WM) (left occipital cluster 2). (A) Cluster of voxels (red) in left occipital WM where maltreated animals had significantly lower FA than controls (P < 0.005, uncorrected, ≥ 10 μL volume). In insets, green represents the mean FA skeleton. (B) FA in left occipital WM is negatively correlated with basal cortisol at one month of age (r = −0.479, P = 0.038). (C) FA in left occipital WM is negatively correlated with total aggression in adolescence (r = −0.465, P = 0.045).
Howell et al. Biology of Mood & Anxiety Disorders 2013 3:21 doi:10.1186/2045-5380-3-21