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Early handling attenuates enhancement of glucocorticoid receptors in the prefrontal cortex in an animal model of post-traumatic stress disorder

Sophie A George1*, Stephanie A Stout1, Melissa Tan1, Dayan Knox13 and Israel Liberzon12

Author Affiliations

1 Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109, USA

2 Ann Arbor Veterans Affairs Hospital, 2215 Fuller Road, Ann Arbor, MI 49105, USA

3 Present address: Department of Psychology, University of Delaware, 108 Wolf Hall, Newark, DE 19716, USA

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Biology of Mood & Anxiety Disorders 2013, 3:22  doi:10.1186/2045-5380-3-22

Published: 2 December 2013

Additional files

Additional file 1:

Representative example of a western blot assay. The data presented in this manuscript were obtained from a larger research project that examined the effects of a number of neonatal treatments and single prolonged stress on GR expression in the hippocampus and prefrontal cortex. This additional data file shows a representative example of a western blot assay.

Format: DOCX Size: 2.3MB Download file

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