A priori region of interest: Anterior cingulate cortex. A) Voxel-wise main effect of group for the contrast Match Shapes > Match Faces, along with Match Shapes (Angry distractor) > Match Angry, Match Shapes (Fear distractor) > Match Fear, and Match Shapes (Happy distractor) > Match Happy, showing anterior cingulate cortex (ACC) displayed on statistical F-map at p < 0.05; cluster size >10 contiguous voxels (family-wise error corrected for multiple comparisons across small volumes of interest). Color scale reflects F-score. B) Bar graphs depicting extracted parameter estimates of activation from the ACC ROI activation within each group showing Healthy Controls exhibited ACC activation, whereas, Generalized Social Anxiety Disorder showed no ‘activation’.
Klumpp et al. Biology of Mood & Anxiety Disorders 2013 3:7 doi:10.1186/2045-5380-3-7